ZIC2 Polyclonal Antibody (E-AB-53238)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ZIC2 |
| Abbre | ZIC2 |
| Synonyms | HPE 5, HPE5, Odd paired homolog Drosophila, ZIC2, Zic 2, Zic family member 2, Zic family member 2 (odd paired Drosophila homolog), Zinc finger protein ZIC 2, Zinc finger protein Zic2, Zinc finger protein of the cerebellum 2 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. Localizes in the cytoplasm in presence of MDFIC overexpression. Both phosphorylated and unphosphorylated forms are localized in the nucleus. |
| Concentration | 2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. |
Other Clones
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Other Formats
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Unconjugated
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