ZFP42 Polyclonal Antibody (E-AB-16185)
For research use only.
| Verified Samples |
Verified Samples in WB: A549, K562, PC-3 |
| Dilution | WB 1:200-1:1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ZFP42 |
| Abbre | ZFP42 |
| Synonyms | REX1, REX1 transcription factor, Reduced Expression 1 Protein, Reduced expression protein 1, Rex-1, ZFP42, ZFP42 zinc finger protein, ZNF754, Zfp-42, Zfp42, Zinc finger protein 42 homolog, Zinc finger protein 754, hREX-1 |
| Swissprot | |
| Calculated MW | 35 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Developmental Biology, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1. |
Other Clones
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Other Formats
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Unconjugated
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