YRDC Polyclonal Antibody (E-AB-19369)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse stomach Verified Samples in IHC: Human esophagus cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human YRDC |
| Abbre | YRDC |
| Synonyms | DRIP3, Dopamine receptor-interacting protein 3, FLJ23476, FLJ26165, IRIP, Ischemia/reperfusion inducible protein, Ischemia/reperfusion-inducible protein homolog, RP11-109P14.4, SUA5, hIRIP, mitochondrial, yrdC, yrdC domain containing , yrdC domain containing (E. coli) |
| Swissprot | |
| Calculated MW | 29 kDa |
| Observed MW |
Refer to figures
The actual band is not consistent with the expectation.
Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane. |
| Cellular Localization | Mitochondrion. Membrane. Predominantly localized in the plasma membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | YrdC (yrdC domain containing protein), also known as IRIP (ischemia/reperfusion-inducible protein homolog), SUA5 or DRIP3 (dopamine receptor-interacting protein 3), is a 279 amino acid ubiquitously expressed protein found at highest levels in brain, liver and pancreas. A member of the SUA5 family, yrdC is involved in certain aspects of transporter activity, such as the regulation of efflux transporter activity and cargo assembly. YrdC is a peripheral membrane protein that contains one yrdC-like domain, interacts with RSC1A1 and localizes to mitochondrial and plasma membranes. |
Other Clones
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Other Formats
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Unconjugated
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