Xanthine Oxidase (XOD) Inhibitor Screening Kit (E-BC-D019)
For research use only.
| Detection Principle |
Xanthine oxidase (XOD) is an enzyme that catalyzes hypoxanthine hydroxylation to xanthine and xanthine hydroxylation to uric acid, and is excreted by the kidney. Excessive production or insufficient excretion of uric acid can lead to hyperuricemia. Therefore, the development of XOD inhibitors can be used in the treatment of high uric acid and ventilation diseases. The detection principle of this kit: XOD catalyzed substrate to produce color substances at 560 nm has a maximum absorption wavelength, after adding inhibitors, the generation of color will be inhibited, according to the degree of inhibition to determine the effect of the inhibitor. |
| Sample Type | Inhibitor |
| Detection Method | Colorimetric method |
| Detection Instrument | Microplate reader (555-565 nm, optimum wavelength: 560 nm) |
| Research Area | Metabolic Diseases , Inhibitor Screening |
| Storage | This product can be stored at -20°C for 12 months with shading light. |
| Valid Period | 12 months |
| Precision | inter-assay CV: 0.9-5.5% | intra-assay CV: 1.2-3.0% |
| Sample Volume | 20 μL |
| Assay Time | 30 min |
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