WWOX Polyclonal Antibody (E-AB-17623)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain Verified Samples in IHC: Human colorectal cancer |
| Dilution | WB 1:500-2000, IHC 1:20-100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human WWOX |
| Abbre | WWOX |
| Synonyms | 5330426P09Rik, 9030416C10Rik, Aberrant WW domain-containing oxidoreductase, D16S432E, EC 1.1.1.-, EIEE28, FOR, FRA16D, Fragile site FRA16D Oxireductase, Fragile site FRA16D oxidoreductase, HHCMA56, MGC55975, PRO0128, Putative oxidoreductase, SCAR12, SDR41C1, Short chain |
| Swissprot | |
| Calculated MW | 47 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Mitochondrion. Golgi apparatus. Partially localizes to the mitochondria. Translocates to the nucleus upon genotoxic stress or TNF stimulation (By similarity). Translocates to the nucleus in response to TGFB1. Isoform 5 and isoform 6 may localize in the nucleus. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology, Epigenetics and Nuclear Signaling, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family.This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene.Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated witHuman, Mouseultiple types of cancer.Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. |
Other Clones
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Other Formats
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Unconjugated
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