VMA21 Polyclonal Antibody (E-AB-53204)

For research use only.
Verified Samples |
Verified Samples in IHC: Human esophagus cancer Verified Samples in IF: HepG2, NCCIT |
Dilution | IHC 1:150-1:500, IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC, IF |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human VMA21 |
Abbre | VMA21 |
Synonyms | Vacuolar ATPase Assembly Factor, MEAX, Myopathy With Excessive Autophagy, Myopathy With Excessive Autophagy Protein, VMA21, VMA21 Vacuolar H+-ATPase, VMA21 Vacuolar H+-ATPase Homolog (S. Cerevisiae), Vacuolar ATPase Assembly Integral Membrane Protein VMA21, XMEA |
Swissprot | |
Cellular Localization | Endoplasmic reticulum, endoplasmic reticulum membrane, Golgi apparatus, ER to Golgi transport vesicle membrane, Lysosome, Other locations: endoplasmic reticulum-Golgi intermediate compartment membrane, integral component of membrane. |
Concentration | 2.6 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cell Biology, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion, affecting boys and sparing carrier females. Onset is in childhood, and patients exhibit weakness of the proximal muscles of the lower extremities, progressing slowly to involve other skeletal muscle groups over time. |
Other Clones
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Other Formats
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Unconjugated
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