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Uncoated Rat IL-6R (Interleukin 6 Receptor) ELISA Kit (E-UNEL-R0062)

All Size Price Qty
96T*5 $ 399.00
96T*15 $ 958.00
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For research use only.

Product Summary

The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.

Detection Range 0.78-50 ng/mL
Sample Volume 100 μL
Total Assay Time 24 h
Reacitivity Rat
Specificity This kit recognizes Rat IL-6R in samples.No significant cross-reactivity or interference between Rat IL-6R and analogues was observed
Recovery 80%-120%
Sample Type Serum, plasma
Detection Method Colorimetric method, ELISA, Sandwich
Size 96T*5 / 96T*15
Storage -20℃
Expiration Date 12 months
Part of the receptor for interleukin 6. Binds to IL6 with low affinity,but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response,acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling',the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively,'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
Uniport ID P22272
Research Area Cell Biology , Immunology , Innate Immunity , Neuroinflammation , Neuroscience , Signal Transduction , Stem Cells
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