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Uncoated Human TACE/ADAM17 (TNF α Converting Enzyme) ELISA Kit (E-UNEL-H0367)

All Size Price Qty
96T*5 $ 399.00
96T*15 $ 958.00
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For research use only.

Product Summary

The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.

Detection Range 0.16-10 ng/mL
Sample Volume 100 μL
Total Assay Time 24 h
Reacitivity Human
Specificity This kit recognizes Human TACE/ADAM17 in samples.No significant cross-reactivity or interference between Human TACE/ADAM17 and analogues was observed
Recovery 80%-120%
Sample Type Serum, plasma
Detection Method Colorimetric method, ELISA, Sandwich
Size 96T*5 / 96T*15
Storage -20℃
Expiration Date 12 months
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor. This protease also functions in the processing of numerous other substrates, including cell adhesion proteins, cytokine and growth factor receptors and epidermal growth factor (EGF) receptor ligands. The encoded protein also plays a prominent role in the activation of the Notch signaling pathway. Elevated expression of this gene has been observed in specific cell types derived from psoriasis, rheumatoid arthritis, multiple sclerosis and Crohn's disease patients, suggesting that the encoded protein may play a role in autoimmune disease.
Uniport ID P78536
Research Area Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction, Stem Cells
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