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Uncoated Human PECAM1/CD31 (Platelet/Endothelial Cell Adhesion Molecule 1) ELISA Kit (E-UNEL-H0357)

All Size Price Qty
96T*5 $ 399.00
96T*15 $ 958.00
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For research use only.

Product Summary

The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.

Detection Range 0.31-20 ng/mL
Sample Volume 100 μL
Total Assay Time 24 h
Reacitivity Human
Specificity This kit recognizes Human PECAM1/CD31 in samples.No significant cross-reactivity or interference between Human PECAM1/CD31 and analogues was observed
Recovery 80%-120%
Sample Type Serum, plasma
Detection Method Colorimetric method, ELISA, Sandwich
Size 96T*5 / 96T*15
Storage -20℃
Expiration Date 12 months
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions.Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes.Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions.Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils.Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal.Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes.
Uniport ID EAW94208.1
Research Area Cancer , Cardiovascular , Immunology , Signal Transduction , Stem Cells
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