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Uncoated Human PD-1 (Programmed Cell Death Protein 1) ELISA Kit (E-UNEL-H0340)

All Size Price Qty
96T*5 $ 399.00
96T*15 $ 958.00
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For research use only.

Product Summary

The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.

Detection Range 15.63-1000 pg/mL
Sample Volume 100 μL
Total Assay Time 24 h
Reacitivity Human
Specificity This kit recognizes Human PD-1 in samples.No significant cross-reactivity or interference between Human PD-1 and analogues was observed
Recovery 80%-120%
Sample Type Serum, plasma
Detection Method Colorimetric method, ELISA, Sandwich
Size 96T*5 / 96T*15
Storage -20℃
Expiration Date 12 months
Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self.Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.Following T-cell receptor (TCR) engagement; PDCD1 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation.Suppresses T-cell activation through the recruitment of PTPN11/SHP-2: following ligand-binding; PDCD1 is phosphorylated within the ITSM motif; leading to the recruitment of the protein tyrosine phosphatase PTPN11/SHP-2 that mediates dephosphorylation of key TCR proximal signaling molecules; such as ZAP70; PRKCQ/PKCtheta and CD247/CD3zeta.
Uniport ID P_005009.2
Research Area Cancer , Cell Biology , Immunology
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