Uncoated Human α2-M (Alpha-2 Macroglobulin) ELISA Kit (E-UNEL-H0255)
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For research use only.
Product Summary
The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.
Detection Range | 15.63-1000 ng/mL |
Sample Volume | 100 μL |
Total Assay Time | 24 h |
Reacitivity | Human |
Specificity | This kit recognizes Human α2-M in samples.No significant cross-reactivity or interference between Human α2-M and analogues was observed |
Recovery | 80%-120% |
Sample Type | Serum, plasma |
Detection Method | Colorimetric method, ELISA, Sandwich |
Assay Type | Sandwich-ELISA |
Size | 96T*5 / 96T*15 |
Storage | -20℃ |
Expiration Date | 12 months |
Background
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified.
Uniport ID | P01023 |
Research Area | Cancer, Cell Biology, Cardiovascular |
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