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For research use only.

Verified Samples Verified Samples in IHC: Human brain, Human lung cancer
Dilution IHC 1:40-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human UBR4
Abbre UBR4
Synonyms 600 kDa retinoblastoma protein associated factor,  600 kDa retinoblastoma protein-associated factor,  E3 ubiquitin-protein ligase UBR4,  KIAA0462,  KIAA1307,  N-recognin-4,  RBAF600,  Retinoblastoma associated fact,  Retinoblastoma associated factor 600 like protein,  p600
Swissprot
Cellular Localization Membrane. Cytoplasm. Cytoplasm>cytoskeleton. Nucleus. Concentrates at the leading edge of membrane structures involved in actin motility.
Concentration 1.1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Microbiology,  Signal Transduction,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein.
Other Clones

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Unconjugated

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