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For research use only.

Verified Samples Verified Samples in IF: C6, NIH/3T3
Dilution IF 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human TSC2 (NP_000539.2).
Abbre TSC2
Synonyms LAM,  PPP1R160,  TSC2,  TSC4,  Tuberin,  tuberin
Swissprot
Cellular Localization Cytoplasm. Membrane. At steady state found in association with membranes.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Clones

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Unconjugated

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