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For research use only.

Verified Samples Verified Samples in WB: Human muscle
Verified Samples in IHC: Human esophagus cancer
Dilution WB 1:1000-1:5000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human TRIM63
Abbre TRIM63
Synonyms E3 ubiquitin-protein ligase TRIM63,  FLJ32380,  IRF,  Iris RING finger protein,  MURF 1,  MURF-1,  MURF2,  MuRF1,  Muscle specific ring finger protein 1,  Muscle specific ring finger protein 2,  Muscle-specific RING finger protein 1,  OTTHUMP00000008701,  RING finger protein 28
Swissprot
Calculated MW 40 kDa
Cellular Localization Cytoplasm. Nucleus. Localizes to the M- and Z-lines in skeletal muscle. Colocalizes with TNNI3 in myocytes.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Cardiovascular,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
Other Clones

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Other Formats

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Unconjugated

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