TRIM24 Polyclonal Antibody (E-AB-17454)
For research use only.
| Verified Samples |
Verified Samples in WB: 293T, 231, L-O2 Verified Samples in IHC: Human breast cancer |
| Dilution | WB 1:500-2000, IHC 1:30-150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TRIM24 |
| Abbre | TRIM24 |
| Synonyms | E3 ubiquitin protein ligase TRIM24, E3 ubiquitin-protein ligase Trim24, PTC6, RING finger protein 82, RNF82, TF1A, TIF1, TIF1-alpha, TIF1A, TIF1ALPHA, Transcription intermediary factor 1-alpha, Transcriptional , Transcriptional intermediary factor 1 alpha, hTIF1 |
| Swissprot | |
| Calculated MW | 117/113 kDa |
| Cellular Localization | Nucleus. Cytoplasm. Colocalizes with sites of active transcription. Detected both in nucleus and cytoplasm in some breast cancer samples. Predominantly nuclear. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. |
Other Clones
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Other Formats
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Unconjugated
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