TP63 Polyclonal Antibody (E-AB-52639)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human prostate cancer |
| Dilution | IHC 1:50-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human TP63 |
| Abbre | TP63 |
| Synonyms | AIS, Amplified in squamous cell carcinoma, B(p51A), B(p51B), CUSP, Chronic ulcerative stomatitis protein, DN p63 alpha 1, DNp63, EEC3, KET, Keratinocyte transcription factor, Keratinocyte transcription factor KET, LMS, MGC115972, MGC192897, NBP, OFC8, OTTHUMP00, id:ibd3516 |
| Swissprot | |
| Cellular Localization | Nucleus |
| Concentration | 0.72 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | TP63,also named KET,P63,P73H,P73L and TP73L,belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53,the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40),50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain. |
Other Clones
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Other Formats
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Unconjugated
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