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For research use only.

Verified Samples Verified Samples in WB: Jurkat
Verified Samples in IHC: Human liver cancer, Human thyroid cancer
Dilution WB 1:500-1:2000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human TP53I11
Abbre TP53I11
Synonyms PIG 11,  PIG11,  Tumor protein p53 inducible protein 11,  p53 induced gene 11 protein,  p53 induced protein
Swissprot
Calculated MW 21 kDa
Cellular Localization Other locations: integral component of membrane.
Concentration 0.7 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family.The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity.It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis.The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
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Unconjugated

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