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For research use only.

Verified Samples Verified Samples in WB: Mouse kidney, 293T, 231
Verified Samples in IHC: Human thyroid cancer, Human brain
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human TP53BP2
Abbre TP53BP2
Synonyms 53BP2,  ASPP2,  Apoptosis stimulating of p53 protein 2,  Apoptosis stimulating protein of p53 2,  Apoptosis-stimulating of p53 protein 2,  BBP,  Bcl2 binding protein,  Bcl2-binding protein,  NY REN 51 antigen,  PPP1R,  p53 binding protein 2,  p53-binding protein 2,  p53BP2
Swissprot
Calculated MW 126 kDa
Cellular Localization Cytoplasm>perinuclear region. Nucleus. Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
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Unconjugated

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