TOP1 Polyclonal Antibody (E-AB-64227)
For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse liver |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | A synthetic peptide of human TOP1 (NP_003277.1). |
| Abbre | TOP1 |
| Synonyms | TOP1, TOPI |
| Swissprot | |
| Cellular Localization | Nucleus, nucleolus, Nucleus, nucleoplasm, Diffuse nuclear localization with some enrichment in nucleoli, On CPT treatment, cleared from nucleoli into nucleoplasm, Sumolyated forms found in both nucleoplasm and nucleoli. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. |
Other Clones
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Other Formats
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Unconjugated
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