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For research use only.

Verified Samples Verified Samples in IHC: Human stomach carcinoma, Human placenta, Human liver(cirrhosis)
Dilution IHC-P 1:50-1:200,  
Isotype IgG2b
Host Mouse
Reactivity Human
Applications IHC-P
Clonality Monoclonal
Immunogen Recombinant Human Tie1 Protein
Abbre Tie1
Synonyms JTK,  Tyrosine-Protein Kinase Receptor Tie,  TIE1,  JTK14,  TIE,  Tyrosine-Protein Kinase Receptor Tie-1,  Tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Swissprot
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Signal Transduction,  Stem Cells,  Cancer,  Cardiovascular,  Developmental Biology
Clone No. 9D4
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie1 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Unconjugated

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