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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human THG1L
Abbre THG1L
Synonyms ICF45,  Interphase cytoplasmic foci protein 45,  Probable tRNA(His) guanylyltransferase,  THG1,  THG1L,  tRNA histidine guanylyltransferase 1 like (S. cerevisiae),  tRNA-histidine guanylyltransferase
Swissprot
Cellular Localization Cytoplasm. Found near the nuclear membrane.
Concentration 0.9 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
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Unconjugated

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