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For research use only.

Verified Samples Verified Samples in IHC: Rat brain, Mouse brain
Verified Samples in IF: Jurkat, Mouse brain, Rat brain
Dilution IHC 1:50-1:200,  IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human TH (NP_000351.2).
Abbre TH
Synonyms DYT14,  DYT5b,  TH,  TYH
Swissprot
Cellular Localization Cytosol, Endoplasmic reticulum, smooth endoplasmic reticulum, Mitochondrion, Nucleus, Plasma Membrane, cytoplasmic side of plasma membrane, Other locations: cytoplasm, cytoplasmic vesicle, dendrite, melanosome membrane, neuron projection, perikaryon, synaptic vesicle, terminal bouton.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Other Clones

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Unconjugated

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