STARD4 Polyclonal Antibody (E-AB-53335)

For research use only.
Verified Samples |
Verified Samples in IHC: Human tonsil |
Dilution | IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human STARD4 |
Abbre | STARD4 |
Synonyms | 4632419C16Rik, 9030213J02Rik, AA517649, AW324468, STAR4, START domain containing 4 sterol regulated, START domain-containing protein 4, StAR related lipid transfer (START) domain containing 4, StAR-related lipid transfer protein 4, StARD4 |
Swissprot | |
Concentration | 1.2 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Signal transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]). |
Other Clones
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Other Formats
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Unconjugated
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