SPRTN Polyclonal Antibody (E-AB-52495)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human ovarian cancer |
| Dilution | IHC 1:50-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human SPRTN |
| Abbre | SPRTN |
| Synonyms | C1orf124, CA124, Chromosome 1 open reading frame 124 , DDDL1880, PRO4323, RP5-876B10.3, Spartan, SprT-like N-terminal domain, SprT-like domain at the N terminus, Zinc finger RAD18 domain-containing protein C1orf124, dJ876B10.3 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified. |
Other Clones
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Other Formats
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Unconjugated
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