SPHK2 Polyclonal Antibody (E-AB-10958)

For research use only.
Verified Samples |
Verified Samples in WB: Mouse brain, Mouse liver Verified Samples in IHC: Human thyroid cancer |
Dilution | WB 1:200-1:1000, IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human SPHK2 |
Abbre | SPHK2 |
Synonyms | SK 2, SPHK2, SPK 2, Sphingosine kinase 2, Sphingosine kinase type 2 |
Swissprot | |
Calculated MW | 69 kDa |
Cellular Localization | Cytoplasm. Membrane and Lysosome membrane. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate.Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis.The encoded protein may play a role in breast cancer proliferation and chemoresistance.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Other Clones
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Other Formats
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Unconjugated
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