SPDEF Polyclonal Antibody (E-AB-10535)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human tonsil |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SPDEF |
| Abbre | SPDEF |
| Synonyms | PDEF, PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR, PSE, Prostate derived Ets factor, Prostate epithelium-specific Ets transcription factor, Prostate specific Ets, Prostate-derived Ets factor, Prostate-specific Ets, RP11-375E1__A.3, SAM POINTED , bA375E1.3 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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