SNAP25 Polyclonal Antibody (E-AB-60128)
For research use only.
| Verified Samples |
Verified Samples in IF: HeLa |
| Dilution | IF 1:20-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human SNAP25 (NP_003072.2). |
| Abbre | SNAP25 |
| Synonyms | CMS18, RIC-4, RIC4, SEC9, SNAP, SNAP-25, SNAP25, SUP, bA416N4.2, dJ1068F16.2 |
| Swissprot | |
| Cellular Localization | Cytoplasm>perinuclear region. Cell membrane. Cell junction>synapse>synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. |
Other Clones
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Other Formats
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Unconjugated
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