SLC7A11 Polyclonal Antibody (E-AB-17625)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human brain, Human thyroid cancer |
| Dilution | IHC 1:20-100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SLC7A11 |
| Abbre | SLC7A11 |
| Synonyms | Amino acid transport system xc xCT, Amino acid transport system xc-, CCBR1, Calcium channel blocker resistance protein CCBR1, Cysteine/glutamate transporter, Cystine/glutamate transporter, OTTHUMP00000164578, SLC7 |
| Swissprot | |
| Calculated MW | 55 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. |
Other Clones
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Other Formats
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Unconjugated
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