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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human SIX6
Abbre SIX6
Synonyms Homeobox protein SIX6,  Homeodomain protein OPTX2,  MCOPCT 2,  MCOPCT2,  OPTX 2,  OPTX2,  Optic homeobox 2,  SIX 6,  SIX homeobox 6,  SIX6,  Sine oculis homeobox homolog 6,  Six 9,  Six6,  Six9
Swissprot
Cellular Localization Nucleus
Concentration 1.44 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Epigenetics and Nuclear Signaling,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).SIX6 (SIX Homeobox 6) is a Protein Coding gene. Diseases associated with SIX6 include Optic Disc Anomalies With Retinal And/Or Macular Dystrophy and Six6-Related Eye Disorders. Among its related pathways are Ectoderm Differentiation. GO annotations related to this gene include transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is SIX3.
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Unconjugated

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