SETMAR Polyclonal Antibody (E-AB-18994)

For research use only.
Verified Samples |
Verified Samples in IHC: Human esophagus cancer |
Dilution | IHC 1:50-1:300 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human SETMAR |
Abbre | SETMAR |
Synonyms | Histone lysine N methyltransferase, Histone lysine N methyltransferase SETMAR, Hsmar 1, Hsmar1, Mariner transposase Hsmar1, Metnase, SET domain and mariner transposase fusi, SET domain and mariner transposase fusion, SET domain and mariner transposase fusion gene |
Swissprot | |
Cellular Localization | Nucleus. Chromosome. |
Concentration | 1.08 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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