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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human SETMAR
Abbre SETMAR
Synonyms Histone lysine N methyltransferase,  Histone lysine N methyltransferase SETMAR,  Hsmar 1,  Hsmar1,  Mariner transposase Hsmar1,  Metnase,  SET domain and mariner transposase fusi,  SET domain and mariner transposase fusion,  SET domain and mariner transposase fusion gene
Swissprot
Cellular Localization Nucleus. Chromosome.
Concentration 1.08 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Other Clones

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Unconjugated

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