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For research use only.

Verified Samples Verified Samples in IHC: Human gastric cancer, Human esophagus cancer
Dilution IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human SETD1A
Abbre SETD1A
Synonyms Histone-lysine N-methyltransferase SETD1A,  KMT2F ,  Lysine N methyltransferase 2F,  Lysine N-methyltransferase 2F,  SET domain containing 1A,  SET domain containing protein 1A,  SET domain-containing protein 1A,  SET1 ,  Set1 Ash2 histone methyltransferase comple,  hSET1A
Swissprot
Cellular Localization Nucleus speckle. Chromosome. Localizes to a largely non-overlapping set of euchromatic nuclear speckles with SETD1B, suggesting that SETD1A and SETD1B each bind to a unique set of target genes.
Concentration 0.72 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.
Other Clones

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Unconjugated

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