SETD1A Polyclonal Antibody (E-AB-18095)

For research use only.
Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human esophagus cancer |
Dilution | IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human SETD1A |
Abbre | SETD1A |
Synonyms | Histone-lysine N-methyltransferase SETD1A, KMT2F , Lysine N methyltransferase 2F, Lysine N-methyltransferase 2F, SET domain containing 1A, SET domain containing protein 1A, SET domain-containing protein 1A, SET1 , Set1 Ash2 histone methyltransferase comple, hSET1A |
Swissprot | |
Cellular Localization | Nucleus speckle. Chromosome. Localizes to a largely non-overlapping set of euchromatic nuclear speckles with SETD1B, suggesting that SETD1A and SETD1B each bind to a unique set of target genes. |
Concentration | 0.72 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily. |
Other Clones
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Other Formats
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Unconjugated
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