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For research use only.

Verified Samples Verified Samples in IHC: Human liver damage, Human colon carcinoma
Verified Samples in IF: HeLa
Dilution IHC 1:50-1:200,  IF 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human SECISBP2 (NP_076982.3).
Abbre SECISBP2
Synonyms SBP2,  SECISBP2
Swissprot
Cellular Localization Nucleus.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
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Unconjugated

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