S100A4 Monoclonal Antibody (E-AB-70355)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human lymphoma, Mouse colon, Rat brain |
| Dilution | IHC 1:200-1:800 |
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein corresponding to Mouse S100A4 |
| Abbre | S100A4 |
| Synonyms | 18A2, 42A, CAPL, Calvasculin, FSP1, Fibroblast specific protein, Fibroblast specific protein 1, Fibroblast specific protein 1 (FSP1), Leukemia multidrug resistance associated protein, Malignan, Malignant transformation suppression 1 (MTS1), calcium Placental protein |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Signal Transduction |
| Clone No. | 3A6H9 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer. |
Other Clones
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Other Formats
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Unconjugated
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