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For research use only.

Verified Samples Verified Samples in IHC: Human breast cancer, Human spleen
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human S100A12
Abbre S100A12
Synonyms CAAF1,  CAGC,  CGRP,  Calcitermin,  Calcium-binding protein in amniotic fluid 1,  Calgranulin C,  Calgranulin-C,  Calgranulin-related protein,  EN RAGE,  EN-RAGE,  ENRAGE,  Extracellular newly identified RAGE-binding protein,  MRP6,  N,  migration inhibitory factor-related protein 6
Swissprot
Cellular Localization Cytoskeleton, Cytosol, Extracellular region or secreted, extracellular region, Nucleus, Plasma Membrane, Other locations: cytoplasm, secretory granule lumen.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities.
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Unconjugated

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