RRM1 Monoclonal Antibody (PA7211)

For research use only.
Host | Rabbit |
Reactivity | Human |
Applications | IHC-P |
Synonyms | RRM1 |
Cellular Localization | Cytoplasm |
Tissue Specificity | Breast cancer |
Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
Shipping | Ice bag |
background | Nucleoside diphosphate reductase large subunit (RRM1) is one of two distinct subunits that comprise nucleoside diphosphate reductase. This enzyme is essential for the production of deoxyribonucleotides prior to S-phase DNA synthesis in dividing cells. RRM1 may reflect carcinogenesis and tumor progression. RRM1 expression is highly correlated with ERCC and PTEN expression in non-small cell lung cancer. Rrm1-positive tumors predicted slow progression. |
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