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For research use only.

Verified Samples Verified Samples in IHC: Human brain, Human colon cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
ClonalityPolyclonal
ImmunogenSynthetic peptide of human RRAD
AbbreRRAD
SynonymsGTP binding protein RAD,  GTP-binding protein RAD,  RAD,  RAD1,  RAS (RAD and GEM) like GTP binding 3,  REM3,  RRAD,  Ras associated with diabetes,  Ras related associated with diabetes
Swissprot
Cellular LocalizationCell membrane.
Concentration0.2 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAffinity purification
Research AreasCardiovascular,  Signal Transduction
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundThe protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated