RPA2 Polyclonal Antibody (E-AB-17006)

For research use only.
Verified Samples |
Verified Samples in WB: Hela, HUVEC, HepG2, A549, Jurkat, 231, A431 Verified Samples in IHC: Human breast cancer |
Dilution | WB 1:500-2000, IHC 1:30-150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Full length fusion protein |
Abbre | RPA2 |
Synonyms | 32kDa, 60S acidic ribosomal protein P1, AA409079, AI325195, AU020965, M(2)21C, MGC137236, OTTHUMP00000004008, RCJMB04_6d17 replication protein A2, REPA2, Replication factor A protein 2, Replication protein A, Replication protein A 32 kDa subunit, ik:tdsubc_2g1, p32, p34 |
Swissprot | |
Calculated MW | 29 kDa |
Cellular Localization | Nucleus. Nucleus>PML body. Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage. |
Concentration | 0.7 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Replication protein A 32 kDa subunit is a protein that in humans is encoded by theRPA2 gene.As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. |
Other Clones
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Other Formats
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Unconjugated
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