RNF115 Polyclonal Antibody (E-AB-18328)

For research use only.
Verified Samples |
Verified Samples in IHC: Human liver cancer, Human prostate cancer |
Dilution | IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Full length fusion protein |
Abbre | RNF115 |
Synonyms | BCA2, Breast cancer associated gene 2, CL469780, E3 ubiquitin-protein ligase RNF115, RING finger protein 115, RN115, RNF115, Rabring 7, Zinc finger protein 364 |
Swissprot | |
Cellular Localization | Cytoplasm>cytosol. The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Cell Biology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4. |
Other Clones
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Other Formats
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Unconjugated
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