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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human RITA1
Abbre RITA1
Synonyms C12orf52 ,  Chromosome 12 open reading frame 52 ,  RBPJ interacting and tubulin associated 1,  RBPJ interacting and tubulin associated protein 1,  RBPJ-interacting and tubulin-associated protein,  RITA
Swissprot
Cellular Localization Cytoplasm. Nucleus. Cytoplasm>cytoskeleton>centrosome. Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear.
Concentration 0.9 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Developmental biology,  Neuroscience,  Signal transduction,  Stem cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Other Clones

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Unconjugated

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