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For research use only.

Verified Samples Verified Samples in IHC: Mouse retina
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen A synthetic peptide of human RHO (NP_000530.1).
Abbre RHO
Synonyms CSNBAD1,  OPN2,  RHO,  RP4,  rhodopsin
Swissprot
Cellular Localization Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
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Unconjugated

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