Recombinant XPNPEP2 Monoclonal Antibody (AN300084P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human kidney |
| Dilution | IHC-P 1:50-1:200, |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Rabbit Monoclonal |
| Immunogen | Recombinant Human XPNPEP2 protein |
| Abbre | XPNPEP2 |
| Synonyms | X-Pro Aminopeptidase, Xaa-Pro Aminopeptidase, Xpnpep, Aminoacylproline Aminopeptidase, mAmP, Membrane-Bound Aminopeptidase P, Membrane-Bound AmP, Membrane-Bound APP, Xaa-Pro Aminopeptidase 2, X-Pro Aminopeptidase 2, XPNPEP2 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Signal Transduction, Cell Biology, Metabolism |
| Clone No. | 12G13 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form of this enzyme (XPNPEP2) have been identified as products of two separate genes. XPNPEP2, the X-linked gene that encodes membranous aminopeptidase P (APP), has been reported to associate with APP activity. The membrane aminopeptidase P (XPNPEP2) is largely limited in distribution to endothelia and brush border epithelia. APP and XPNPEP2 contain homologous blocks of sequence common to members of the "pita bread-fold" protein family, of which Escherichia coli methionine aminopeptidase is the prototype. The C-2399A variant in XPNPEP2 is associated with reduced APP activity and a higher incidence of AE-ACEi. XPNPEP2 mRNA was detected in fibroblasts that carry the translocation, suggesting that this gene at least partially escapes X inactivation. XPNPEP2 is a candidate gene for premature ovarian failure (POF). |
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Unconjugated
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