Recombinant STML2 Monoclonal Antibody (AN301155L)
For research use only.
| Verified Samples | Verified Samples in WB: K562 |
| Dilution | WB 1:2000-1:10000, |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human STML2 protein |
| Abbre | STML2 |
| Synonyms | HSPC, Stomatin like, EPB72 like protein, Paraprotein target, Stomatin (EPB72) like, Stomatin like protein, STOML, OTTHUMP, SLP, STOML2, HSPC108, SLP-2, EPB72 like protein 2, mitochondrial, OTTHUMP00000021320, Paraprotein target 7, SLP 2, STML2_HUMAN, Stomatin (EPB72) like 2, Stomatin like 2, Stomatin like protein 2, SLP2, EPB72-like protein 2, Paratarg 7, STML2, Stomatin-like protein 2, STML2 |
| Swissprot | |
| Calculated MW | 39 kDa |
| Observed MW |
39 kDa
Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane. |
| Cellular Localization | Cell membrane, Peripheral membrane protein, Mitochondrion, Mitochondrion inner membrane, Lipid-anchor, Mitochondrion intermembrane space, Membrane raft, Cytoplasm, cytoskeleton, Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain (PubMed:21746876). Also associates with the actin cytoskeleton and membrane rafts in activated T-cells (PubMed:18641330, PubMed:10713127). A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells (PubMed:22623988). |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Cancer |
| Clone No. | 11G4 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Enables GTPase binding activity; T cell receptor binding activity; and cardiolipin binding activity. Involved in intracellular calcium ion homeostasis; mitochondrion organization; and protein complex oligomerization. Acts upstream of or within T cell receptor signaling pathway. Located in several cellular components, including immunological synapse; membrane raft; and mitochondrial envelope. |
Other Clones
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Unconjugated
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