Recombinant SERCA2 Monoclonal Antibody (AN301264L)

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	100μL	$ 320.00	- +
	50μL	$ 211.00	- +

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Verified Samples	Verified Samples in IHC: Human cardiac muscle
Dilution	IHC 1:200-1:1000
Isotype	IgG,κ
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IHC
Clonality	Monoclonal;Recombinant
Immunogen	Recombinant Human SERCA2 protein
Abbre	SERCA2
Synonyms	ATP2A2/SERCA, SERCA, ATP2A, ATP2B, DAR, DD, SERCA2, ATP2A2/SERCA2, ATP2A2, SERCA2
Swissprot	P16615
Cellular Localization	Endoplasmic reticulum membrane, Multi-pass membrane protein, Sarcoplasmic reticulum membrane, Multi-pass membrane protein.
Concentration	0.2 mg/mL
Buffer	PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Purification Method	Protein A
Research Areas	Signal Transduction, Cardiovascular, Metabolism
Clone No.	6B4
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	Ice bag
background	This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Unconjugated