Recombinant RRM2B/P53R2 Monoclonal Antibody (AN300433P)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil, Human squamous cancer, Human skeletal muscle Verified Samples in IF: Hela |
| Dilution | IHC-P 1:100-1:500, ICC/IF 1:20-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P, ICC/IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human RRM2B/P53R2 protein |
| Abbre | RRM2B |
| Synonyms | P53R, RRM2B, MTDPS8A, MTDPS8B, P53R2 |
| Swissprot | |
| Tissue Specificity | Widely expressed at a high level in skeletal muscle and at a weak level in thymus. Expressed in epithelial dysplasias and squamous cell carcinoma. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Epigenetics and Nuclear Signaling, Cancer, Metabolism |
| Clone No. | 4B11 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described. |
Other Clones
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Other Formats
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Unconjugated
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