Recombinant Rat RUNX2/CBFA1 protein (His Tag) (PDER100202)
For research use only.
| Synonyms | Acute myeloid leukemia 3 protein, CBF-alpha-1, CBFA1, CCD1, CCDAML3, CLCD, ML3, OSF-2, OSF2, PEA2-alpha A, PEA2aA, PEBP2-alpha A, PEBP2aA, RUNX2, oncogene AML-3 |
| Species | Rat |
| Expression Host | E.coli |
| Sequence | Asp127-Ile218 |
| Accession | Q9Z2J9 |
| Calculated Molecular Weight | 10.0 kDa |
| Observed Molecular Weight | 12 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | CBFA1, also called runt-related transcription factor 2 (RUNX2), is an essential transcription factor for the regulation of osteoblast differentiation. The CBFA1 gene potentially encodes several proteins that differ in their N-terminal sequences and transactivation capacities. |
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