Recombinant Rat IL20RB Protein (His Tag) (PKSR030418)
For research use only.
| Synonyms | UNQ, PRO, MGC, DIRS, FNDC, fibronectin type III domain containing, IL-20R, IL20RB, DIRS1, FNDC6, IL-20R2, fibronectin type III domain containing 6, hCG_2022374, IL-20 receptor subunit beta, IL-20RB, IL-20R-beta, interleukin-20 receptor II, Interleukin-20 receptor subunit beta, MGC34923, UNQ557, PRO1114 |
| Species | Rat |
| Expression Host | HEK293 Cells |
| Sequence | Met1-Pro227 |
| Accession | B8K1X9 |
| Calculated Molecular Weight | 24.6 kDa |
| Observed Molecular Weight | 32-36 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 91 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation |
Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20. |
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