Recombinant Rat IL1A/IL-1F1 protein (His Tag) (PDER100226)
For research use only.
| Synonyms | interleukin, Hematopoietin, IL1F1hematopoietin, IL1F, IL-1F, alpha, BAF, Hematopoietin-1, IL1, IL1 alpha, IL-1 alpha, IL1-A, IL-1A, IL1-ALPHA, IL1F1, IL-1F1, IL1F1hematopoietin-1, interleukin 1, interleukin-1 alpha, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha, Il1a, FAF, Hematopoietin 1, IL 1 alpha, IL 1A, IL1, IL1 ALPHA, IL1F1, Interleukin 1 alpha, LAF, LEM, Preinterleukin 1 alpha, Il1a |
| Species | Rat |
| Expression Host | E.coli |
| Sequence | Ser115-Ser270 |
| Accession | P16598 |
| Calculated Molecular Weight | 17.1 kDa |
| Observed Molecular Weight | 16 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | IL-1 alpha (Interleukin-1 alpha) is a cytokine that is induced during microbial exposure and promotes the release of multiple inflammatory mediators and acute phase proteins. It also supports hematopoietic stem cell expansion, promotes neutrophil mobilization from the bone marrow, and promotes osteoclast formation. IL-1 alpha signals through a receptor complex composed of IL-1 RI and IL-1 RAcP. It also binds the decoy receptor IL-1 RII which associates with IL-1 RAcP but does not transduce signaling. |
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