Recombinant Rat IL-2 Protein(GST Tag) (PDER100142)
For research use only.
| Synonyms | POIL, Aldesleukin, Interleukin-2, Involved in regulation of T cell clonal expansion, POIL2, T-cell growth factor, IL 2, IL2, lymphokine, TCGF, interleukin 2, T cell growth factor, Il-2 |
| Species | Rat |
| Expression Host | E.coli |
| Sequence | Ala21-Gln155 |
| Accession | P17108 |
| Calculated Molecular Weight | 40.8 kDa |
| Observed Molecular Weight | 42 kDa |
| Tag | N-GST |
| Bio-activity | Not validated for activity |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
| Background | IL-2 (Interleukin 2) is a critical cytokine in T cell biology. It promotes T cell activation and expansion, the development, maintenance and function of regulatory T cells (Treg), and the differentiation of CD8+ T cells into terminal effector cells and memory cells. IL-2 signals through a receptor complex composed of CD25/IL-2 R alpha, IL-2 R beta, and the Common gamma Chain (gamma c). IL-2 R beta is also a component of the IL-15 receptor complex. Gamma c is also a signaling subunit in the receptors for IL-4, -7, -9, -15, and -21. |
Other Clones
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