Recombinant Rat Clusterin/ApoJ protein (His Tag) (PDER100208)
For research use only.
| Synonyms | AAG4, AP, APOJ, Aging-Associated Gene 4 Protein, Apo-J, Apolipoprotein J, CLI, CLU, Clusterin, Complement Cytolysis Inhibitor, Complement-Associated Protein SP-40, KUB1, Ku70-Binding Protein 1, NA1/NA2, TRPM-2, Testosterone-Repressed Prostate Message 2 |
| Species | Rat |
| Expression Host | E.coli |
| Sequence | Glu22-Arg226 |
| Accession | P05371 |
| Calculated Molecular Weight | 22.4 kDa |
| Observed Molecular Weight | 28 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others. |
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