Recombinant Raf-B Monoclonal Antibody (AN301257L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human prostate |
| Dilution | IHC 1:100-1:500 |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human Raf-B protein |
| Abbre | Raf-B |
| Synonyms | RAFB, BRAF, B-RAF1, B-raf, BRAF1, NS7, RAFB1, serine/threonine-protein kinase B-raf, B-raf, BRAF1, B-RAF1, NS7, RAFB1, serine/threonine-protein kinase B-raf, 94 kDa B raf protein, B raf 1, B Raf proto oncogene, B Raf proto oncogene serine threonine protein kinase, B RAF1, BRAF 1, B-Raf proto-oncogene serine/threonine-protein kinase (p94), cRmil, FLJ95109, MGC126806, MGC138284, Murine sarcoma viral (v-raf) oncogene homolog B1, Murine sarcoma viral v raf oncogene homolog B1, Oncogen BRAF, oncogene BRAF1, p94, proto-oncogene B-Raf, Proto-oncogene c-Rmil, RAFB 1, RMIL, serine/threonine kinase, v raf murine sarcoma viral oncogene homolog B, v raf murine sarcoma viral oncogene homolog B1, v-Raf murine sarcoma viral oncogene homolog B1, Raf-B |
| Swissprot | |
| Cellular Localization | Nucleus, Cytoplasm, Cell membrane, Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Cell Biology, Signal Transduction, Cancer |
| Clone No. | 5H4 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
Other Clones
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Other Formats
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Unconjugated
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